you have no control of hepatitis B cirrhosis (liver cirrhosis) disease progression in the prescription or prescriptions of the proprietary Chinese medicines?
Answer:
If the liver function of chronic hepatitis B and HBV-DNA abnormalities will develop long-term cirrhosis
Should be the basis of clinical types, etiology of the different types take different therapeutic measures. The general principle is: a proper rest, rational nutrition mainly supplemented by selective use of drugs. Shouldɾto prevent fatigue and to avoid the application of liver damage drug. medication to master not wish Jane fan.
1. The treatment of acute hepatitis
Strict bed rest early the most important, a notable improvement in symptoms can be a gradual increase in the volume of activities in order to not feel the principle of fatigue, treatment to the symptoms disappeared, isolation expired, may be discharged with normal liver function. After 13 months of rest and gradually return to work.
Diet in order to meet the patients with taste, the light easy to digest food better. Shall contain a variety of vitamins, has enough heat and the right amount of protein, fat should not be too restrictive. Such as eating less or haveŻ, application of 10% glucose solution 10001500ml add Vitamin C3g, liver too Lok 400mg, ordinary insulin-816U, intravenous drip, daily one time. can be added to the mixture of energy and 10% potassium chloride. thermogravimetry were available stomach bacteria Ling Chen Decoction; both were hot and humid with bacteria Chen Artemisia Ling together soup and gastric side addition and subtraction; those with liver depression Xiaoyao; spleen wet storm were usedƽθɢ. those who have advocated deep jaundice Chishao effective reuse. general acute hepatitis curable.
II. The treatment of chronic hepatitis
Mainly include anti-viral replication, improve immune function, protect liver cells and promote regeneration, as well as traditional Chinese medicine treatment, basic treatment and psychological therapy, such as combined therapy. Due to illness easily repeated and sustained positive indicator of HBV replication, may choose the following methods :
1. Antiviral therapy
Of chronic HBV infection, viral replication continued positive indicators, anti-viral treatment is an important measure. At present, antiviral drugs, the effect is not satisfied. Applications can be temporarily inhibited HBV replication, this inhibition disappeared after stopping to make the original indicators was inhibited back to the original level. Some drugs slower, take longer time to see the effect. because of the efficacy of antiviral drugs is limited, and only if active viral replication can be markedly effective, so in recent years, the treatment of chronic hepatitis B hepatitis tend combined to improve efficacy.
(1) IFN (Interferons, IFN) are currently recognized to have a role in HBV replication drugs. And its mechanism are as follows: to block virus propagation and reproduction, primarily through antiviral protein (AVP), resulting in mRNA cleavage, to prevent HBV replication; induced infected liver cell membrane antigen expression of MHC class . Tc cells to promote the identification and destruction effects. At present, the main clinical use of genetic engineering interferon, including interferon -1b, -2a, -2b. reorganization interferon -2b (interference can, Intron A): each 3,000,000 U, intramuscular injection, daily one time once a day, one week later changed to 1 times 36-month course of treatment. HBeAg and HBV-DNA negative conversion rates of up to 3070%, the effect of inhibiting HBV replication sure. but still the vast majority of sustained HBeAg positive, may be associated with HBV-DNA integration-related. 1 type of genetic engineering interferon (interference of Hope): 2,000,600 per ten thousand U, intramuscular injection, daily 1 times, treatment 2 months, the recent 55% rate of HBeAg negative.
The efficacy of interferon, various reports vary, HBeAg negative conversion rate of 40% at 50%. In order to improve the efficacy of corticosteroids useful followed by the removal of interferon, but patients should pay attention to slow a heavier liverlive, or else will enable health to deteriorate. to think by the former C gene mutations in HBV-infected persons, namely, anti-HBe positive, HBV-DNA positive chronic hepatitis, the use of high-dose interferon, efficacy is unsatisfactory. and IFN- effect on HBV replication than -IFN.
Factors that affect the response to interferon therapy: slower than the slow transfer of live liver liver; good effect more women than men; ALT elevated ALT were more effective than normal; HBsAg, HBeAg, HBV-DNA better efficacy of the lowest-effect; unused and antiviral efficacy of immunosuppressive agents are better than those who used invalid; dose and course of treatment, large doses and long treatment seems better.
Side effects and treatment duration, dose-related. The most common are "influenza-like syndrome," manifested as chills, fever, headache, body aches, fatigue and so on. But to continue the application or after the regular gradually reduce the reduction. Many as one-off nature fever, common in the first dose was not found and efficacy relationship. also can cause neutropenia, thrombocytopenia and so on, often after stopping natural recovery, should not affect the treatment. At present, many think with other antiviral or immunomodulatory drugs combined, may enhance efficacy.
(2) Acyclovir (Acyclovir, ACV, homemade Aptian Galloway): the drug for nucleoside analogues, for a variety of DNA viruses have a disincentive to it in the body by the thymidine kinase (TK) activation changes with Su-resistant phosphatase activity in three acycloguanosine, which can inhibit the virus DNAp and DNA chain extension of the suspension of the role of TK and therefore has the role of viruses such as herpes simplex virus better, HBV does not have TK, so the role of the general, many think interferon combined with better efficacy. usage daily 15mg/kg, points on the afternoon diluted intravenous drip, continuous 2 hours, 1 times daily, once a 30, then on the 15th stop on the 15th reuse, treatment at 60 day. domestic reporting efficacy of different effects than -interferon.
(3) Vidarabine (Ara-A) and Ara-AMP (Ara-AMP), both of which are purine analogues that can selectively inhibit HIV DNAP and nucleotide reductase activity, to prevent DNA virus replication. because of Ara-A, Ara-AMP side effects, in recent years have been less.
(4) Polyinosinic cell (PolyI: C): for the synthetic interferon inducer, the domestic application of the relatively longer time, efficacy has not been able to definitely. The efficacy of chronic hepatitis B is not significant. Usage for 4mg, intramuscular injection, 2 per week times, treatment of 36 months.
2. Immunomodulatory drugs aims to enhance anti-viral immunity.
(1) Thymosin: effects of cAMP, through enhanced T cell activity. Usage daily 1020mg, intramuscular injection or intravenous drip, treatment of 23 months.
(2) interleukin-2 (IL-2) can stimulate the immune effector cell proliferation and induced -interferon. Usage daily 10002000U, intramuscular injection, 1 times daily, day treatment 2856. HBeAg negative in some patients.
(3) of lymphokine-activated killer cells ((Lymphokine-activited Killer Cell, referred to as LAK cells), line with lymphokines (such as IL-2 and -IFN) to stimulate their precursor cells are derived from. Internal report will enable some patients HBeAg and HBV-DNA negative.
3. The protection of liver cells of drug
(1) Yiganling by silymarin grass seed saponins extracted corpus luteum may be the stability of liver cell membrane, and promote liver regeneration. Usage for each of 2, 3 times a day course in March.
(2) strong Nanjing extracted from Glycyrrhiza glycyrrhizin on carbon tetrachloride-induced liver toxicity as effective in the treatment of hepatitis, the role to JiangMei better rebound after discontinuation. Existing similar products Ganlixin injection that having studied the effect of superior strength Jiangmei Nanjing. usage add 10% for the 150mg intravenous infusion of glucose, 1 times daily, course of 12 months, pay attention to heart, kidney failure, severe hypokalemia, hypernatremia syndrome Ban used. pregnant women and infants and young children should not use.
(3), oleanolic acid tablets: use as 80mg, 3 times a day using it, treatment in March. Bifendate, usage for the 1525mg, 3 times a day using it, after the reduction to maintain normal transaminases, course of treatment in June. Are role has JiangMei.
Three. The treatment of severe hepatitis
Refer to the treatment of fulminant hepatic failure part.
Iv. The treatment of asymptomatic HBsAg carriers
Where indicators have positive HBV replication, the application of antiviral treatment, the preferred -IFN.
In conclusion, hepatitis B antiviral therapy, the drug studies have indicated that the key lies in its ability to inhibit HBV drug of supercoiled covalently closed circular DNA (ccc DNA), while the existing antiviral drugs on liver nuclei of virus cccDNA no role Therefore, after stopping to re-cccDNA workers for viral replication in the transcription of the template, viral replication. recent hepatitis biological targeting therapy have reported that antisense RNA can be closed to the public key encryption viral replication gene, the level of this gene targeted therapy may give hepatitis B treatment brings new hope. so the treatment of hepatitis B needs to pay attention to symptomatic supportive therapy, combined therapy of Chinese and Western medicines
Diet health and treatment of hepatitis B therapeutic side
Abrus mollis drink
[The use of materials] 30 grams Abrus mollis Scutellaria barbata 15 gramsС30 grams lean pork LOO grams 10 grams ginger 5 jujube
[Production]
(1) lean pork Wash, cut into small pieces. Other materials used for clean (a big ginger,Сfirst soaking 1 hour).
(2) Add all the materials used pot, add water, amount of text1.5-2 hour, seasoning with salt, with the volume of drinking.
[Efficacy] Qingre Qushi, cholagogic Tuihuang.
[Indications] belong to icteric hepatitis B in liver and gallbladder damp-heat from blood knot. Certification body head see all yellow, the color clear, throat pain, urination short, heavy storm heads, chest swelling of the liverfull, greasy yellow tongue coating, the pulse string Slip a few.
[Note] This rule permits parties belong to liver and gallbladder damp-heat stasis in the yang knot yellow card.Qingrejiedu, Qushi Huazhuo, cholagogic Tuihuang. Fangzhong Abrus mollis for leguminous plants with root Guangdong˼Herba , sexual sweet cooler Qingre good advantage to be wet, Jiedu Quyu back jaundice, clinical use can be shown that a singleñƷacute jaundice hepatitis; Labiatae Scutellaria barbata plants for the whole plant of Scutellaria barbata, Weixinof bitter, good Qingre dampness, activating blood and detoxification can be damp-heat jaundice governance;Сsweet ping of acid, beneficial wetlands of reactive Jiedu Tuihuang. on the drug combination, can enhance Qushi Huazhuo, clearing away heat and toxic, cholagogic Tuihuang role. lean pork, ginger, jujube compatible applications, plays a flavoring and in the role of eating appetizers.
[Note]
(1) use of the head side to put their lives at all yellow, the color clear, yellow greasy tongue coating, slippery pulse string a few belong to liver and gallbladder damp-heat for the main points. Yin Wong who wish to this side.
(2) the seeds of Abrus mollis toxic when used to remove the beans Britain, in order to prevent poisoning.
(3) in light of the appropriate diet, avoid spicy Sunburn and frozenʸthe buck of goods; quit alcohol; flirt Zhi.
Participation to the mutton soup
[The use of materials] dangshen 15 grams of Angelica 10 grams medlar 15 grams mutton 150 grams ginger 10 grams Jujuba 10
[Production]
(1) Wash mutton,նsmall. The rest of the material to be used all the clean (a big ginger), back-up.
(2) Add all the materials used pot, add water, amount of text2.53 hours, seasoning with salt, with the volume of drinking.
[Efficacy] Jianpi liver.
[Indications] chronic hepatitis B who belong to the liver and spleen deficiency.ƣcard see fatigue, loss of appetite, limb fatigue, abdominal painв,ϥlanguid,צwhitish, pale tongue, thin white coating, pulse string fine and ease.
[Note] This rule permits many parties a long time because of liver and spleen, caused by liver and spleen deficiency, qi and blood deficiencies, loss of limbsٺdependent on the wing, they are emergingƣfatigue, limb fatigue, loss of appetite, etc. no later than minus card. Governance Yi Jianpi liver, Yiqi Yangxue. Fangzhong dangshen for Campanulaceae Codonopsis perennial herb of dry root, sexual Ping sweet, good Qi Gong Yangxue Health Law, pharmacological studies show that the goods contain saponins, trace alkaloids, carbohydrates, vitamins B1, B2, a variety of essential inorganic elements and amino acids and so on, to have excited the role of the nervous system, can enhance the body resistance exercise, such as with the regulation of gastrointestinal function, clinical use show that the goods have Hugan role. Danggui for Umbelliferae perennial herb angelica root, sweet and warm Sim, for the blood to drugs, pharmacological studies have proved the goods caused by carbon tetrachloride in mice has a protective effect on liver injury and promote liver regeneration and restore some function of the liver. arrest handle sexual Ping sweet, good-gong fill the liver and kidney, essence and blood, pharmacological studies demonstrate its role in promoting hematopoietic function, the liver has the role. on the drug combination, the common starting to Jianpi liver, Yiqi Yangxue effect. QQ-804907762 advisory Baogan best products / / lamb of ping, Buzhong, Jianpi Yangwei, ginger, jujube match with Yangwei and in the seasoning of the gong, and sweet and delicious soup.
[Note]
(1) use of the side toƣmalaise, anorexia, lipA,вabdominal pain, pale tongue, thin white coating, pulse thin and ease string belong to the liver and spleen deficiency, qi and blood deficiencies were the main points. If God tired lazy,ɴŻ, threatening inflation and pain, yellow greasy tongue coating, slippery pulse string or slip a few̽belong to hot and humid, non-desirable by the parties.
(2)ƣfatigue, burnout limbs obviously belong to Qi-deficiency may increase the North-Mao-sheng, 15 grams to help Jianpi Yiqi power.
(3) loss of appetite do not even think of eating, will be added to 30 grams of malt Health Jianweixiaoshi, Shugan Jieyu.
(4) soft stool diarrhea may increase pachyman or 12 grams to 30 grams yam medicine Jianpi Zhixie.
(5) to quit alcohol; Festival sexual, do not overwork.
Shenmai Dihuang Decoction
[The use of materials] Pseudostellaria 30Winter 15 gramsػ15 grams schisandrin 10 grams of lean pork 100 grams Chenpi 10 grams ginger 5 grams Jujuba 10
[Production]
(1) lean pork washedնsmall. The rest of the materials used Wash (Ginger tumultuous), back-up.
(2) Add all the materials used pot, add water, amount of text1.5-2 hour, seasoning with salt, with the volume of drinking.
[Efficacy] Yiqi Yangyin.
[Indications] chronic hepatitis B who belong to Yin Deficiency.ƣcard see tired body fatigue, shortness of breath lazy words and body weight loss, throat and thirst, many Khan,вpain, or have heart palpitations insomnia, red tongue less moss, pulse imaginary number.
[Note] This rule permits parties are a long time because of liver disease, twoinjury,ƣbody tired, shortness of breath Khan many, throat֢imaginary clock.Yiqi Yangyin of Law Health Law. Fangzhong Pseudostellaria for Caryophyllaceae Pseudostellaria perennial herb of the root, sexual Ping bitter sweet, has Buqi benefits of shade-chun Gong; Liliaceae Ophiopogon japonicus perennial herb of the root, good Yangyin Gong Sheng Jin;ػcold bitter sweet, although it is Qingre Liangxue the goods, but it has a good Yangyinֹachievements, pharmacological studies showed that Rehmannia Decoction can protect the liver, to prevent the yuan to reduce the role of glycogen; schisandrin for perennial Magnoliaceae the essence of vine leaves or Schisandra Schisandra sphenanthera the ripe fruit, sweet and warm acid, good Qi Gongֹ, pharmacological research and clinical use show that the goods can lower serum transaminase, the liver cells have protective effect. above medicine taste to match, co-played the gong Yiqi Yangyinֹ. such as the remaining few taste lean pork, dried tangerine peel, ginger, jujube, were playing together Yangwei, and in the seasoning of the gong.
[Note]
(1) use of the side bodyƣtired, shortness of breath, throat, tongue less red moss, virtual clock for points belong to Yin Deficiency.аif unresolved, or hotSheng andnot injured, although the body tiredƣKhan thirst of many disorders, is also not advisable for the application of this side.
(2) if so, what do knot stool may increase to 15 grams figwort Ziyin Tongbian Runzao.
(3) avoid eating spicy and frozen on the goods; quit alcohol.
Sedum Golden Buddha drink
[The use of materials] sarmentosum 30 grams kwangsiensis 10 grams bergamot 10 gramsǮ12 grams escargot 50 Ginger 10 grams Jujuba 10
[Production]
(1) cement with water to go half a day in silence and calm sand, broken beat Shell Remove; other use of materials for clean (a big ginger), back-up.
(2) Add all the materials used pot, add water, amount of text1.5-2 hour, seasoning with salt, with the volume of drinking.
[Efficacy] Qingre dampness, qi pain.
[Indications] without jaundice hepatitis B who belong to liver and gallbladder damp-heat.вʹcard see pain, chest tightnessɴ, nausea, vomiting, bulging earĿ, urine red, yellow, slightly greasy yellow mamillata moss, pulse a few strings Waterloo .
[Note] This rule permits parties are hot and humid because of̽in the liver and gallbladder, liverestranged, gall bladder notй, itвʹpain; hot and humid in the resistance, abnormal movements, they are triggeredŻchest tightness.Qingre dampness , Shugan Qi pain. Fangzhong sarmentosum for Sedum succulent perennial herb sarmentosum wholly grass, and cool slightly acidic sweet light, dampness Tuihuang Zhigong good, clearing away heat and toxic, pharmacological research and clinical use showed that This product has a role in the liver and reduce the role of alanine aminotransferase, a single oral tabletñƷtreatable acute and chronic hepatitis;Ǯfor Primulaceae Lysimachia perennial herb of the whole plant, sweet light of, good diuretic detoxification, liver and gallbladder fire clearance; II drug match Qingre dampness power can be strengthened. The main evidence for Fangzhongвʹ, it also selected kwangsiensis, bergamot Shugan Qi pain; kwangsiensis for perennial Zingiberaceae Plantgold, turmeric, Guangxi Ezhu or pont Ezhu the root, cold bitter Sim, qi gong good pain relief, Qingre cholagogic; bergamot for Rutaceae evergreen small tree or shrub plant fruit bergamot, bitter and warm Weixin , Gong-good Shugan Jieyu, the gas pain, and can manage its gas and Medium, phlegm dampness, two drugs combined, so that liver qi analgesic power to be strengthened. escargot Qingre dampness, ginger, jujube match, tune medicine appetizer, soup so delicious.
[Note]
(1) use of the side toвʹpain, urination ecliptic, mamillata, little yellow greasy moss, pulse a few strings belong to Waterloo for liver and gallbladder damp-heat points.вif pain, throat thirst, red tongue less moss, pulse string breakdown of kidney-yin deficiency and those who belong to the liver, should not use this side.
(2) Without sarmentosum can diffusa Dandelion 30 grams or 15 grams on behalf of, the choice of reactive Qingre Jiedu dampness.
(3) chest tightness obviousŻmay Jiachun villosum 6 grams.
(4) diet during the period in order to light the appropriate diet, avoid spicy and cold Sunburnʸresponsibility of frozen goods. Quitting alcohol; flirt Zhi.
Jaundice-type hepatitis B-I side
[The use of materials] 15 grams capillaris Herba 15 grams Talc 20 grams jujube 10 Paramisgurnus 150 grams of white radish 150 grams ginger 10 grams
[Creation]
(1) loach go gills and viscera, Wash; talc fried with gauze pack; the remaining material to be used as wash (white radish cut blocks, a big ginger).
(2) Add all the materials used pot, add water, amount of text1.5-2 hours, to Paramisgurnus, seasoning with salt, with the volume of drinking.
[Efficacy] Qingre advantage to be wet, and stomach Huazhuo.
[Indication] of acute jaundice hepatitis B who belong to hot and humid are sung. Permit see heads are yellow body, and its distinctive color, body hot thirst, short yellow urine, dry mouth suffering, the hardship of the first body weight, chest fullswelling of the liver, Do faeces, greasy yellow tongue coating, slippery pulse a few strings.
[Note] This rule permits side was particularly prevalent in the hepatitis B patients with acute jaundice. Its etiology are due to pay steaming hot and humid, hot may not be outside more, wetlands may not be discharged, wetlands evil Yu steaming hot with the blood in the skin, they are a face appears all yellow , urine and other disadvantaged.Qingre dampness, supplemented by qi and stomach Huazhuo. Fangzhong for Asteraceae capillaris capillaris perennial herb or Scoparone's so the whole plant, bitter taste of, reactive tertiary Kiyotoshi hot and humid cholagogic Tuihuang for jaundice to drug administration. pharmacological research show that: capillaris have a significant choleretic effect, increasing bile secretion also increase bile solids, acid and bilirubin excretion; and antipyretic and blood pressure. can be seen that the treatment of jaundice capillaris has its basic pharmacological and reliable. plantain for the car before the former perennial herb or flat car in front of the whole plant, cold sweet, goodʪdiuretic, Qingre detoxification, and Yinchen match, and its diureticʪenhance the power of heat-clearing and detoxifying. hydrotalcite for silicate minerals talc talc tribe, sweet light, cold, good at Qingre Mizuhiki damp profits from the urine out of evil. Paramisgurnus fill in gas, Qushi turbid, white radish under the Gas Consumers Turbidimetry Liqi and Medium. ginger, jujube combination reconcile the spleen and stomach, spleen and stomach in order to restore the Medium Coke Shengqing Jiangzhuo the function of the spleen and stomach health, while the wet muddy from the evil go.
[Note]
(1) use of the side to face an all yellow, yellow, clear urine short red, yellow greasy tongue fur, pulse Shen few belong to liver and gallbladder damp-heat for the main points. Jaundice with dull yellow, or such as smoke,ƣchills, mouth, pale tonguemoss, moisten the pulse is reduced or Shen Chi Yin Wong, non-desirable by the parties.
(2) talc powder for medicine, when to use the gauze decocted loose packet frying, to avoid hard drinkingҩ֭turbidity.
(3) if the wet weight for hot light, card, see the hardship of the first body weight,mouth, chest fullswelling of the liver, abdominal distension, tongue thick and greasy or yellow, moisten a few veins, then use cotton capillaris; if hot re-wet light, dry mouth, see hard evidence, do stool, urine short red, yellow greasy tongue fur, pulse a few strings, then with soil capillaris. because Potaninia capillaris Qingre Qushi power greater than the strength of the soil Qingre capillaris reactive than the reactive Qushi.
(4) wish to quit smoking wine, food and drink appropriate to light, avoid spicy Sunburn and frozen coldʸthe buck on the goods. Emotional stability should be maintained to avoid the angry angry.
Jaundice-type hepatitis B Recipe
[The use of materials] have to corn 60 grams Pig Carex 30Xiexin 10 Kesheng Hui-jobi 60 grams Chenpi 5 grams of beef 100 grams ginger 10 grams Jujuba 10
[Production]
(1) Wash the beef, cut into small pieces. Other material to be used as wash (soak Chenpi go white, a big ginger).
(2) Add all the materials used pot, add water, amount of text2-2.5 hours, seasoning with salt, with the volume of drinking.
[Efficacy] Huazhuo dampness, combined with heat.
[Indications] jaundice-type hepatitis B belong to hot wet weight lighter. Certification body head see all yellow, but not very distinctive yellow, head and body re-trapped chest fullswelling of the liver, anorexia, nausea and vomiting, abdominal distension and urine short , stool soft dirt, Lunatia thick and greasy tongue coating, slippery pulse string or moisten ease.
[Note] This rule permits parties jaundice hepatitis B belong to the wet weight of hot light. Wet hot suppress obstruct, bile does notѭRoad and spillover skin, so bodyĿɫyellow, also forаwet, wet weight of hot light, so the Color is not clear. wet storm spleen, Kin Yun-disorders, Qing Yang hair may not be Vietnam, turbid evil shall not be transported, and disorders caused by air flight and trigger various cards.Qushi Huazhuo, cholagogic Tuihuang, accompanied by Qingre . Fangzhong maize Gramineae have to for one-year-old herb corn stylar and stigma, sexual Ping sweet, good diuresis reactive swelling, dampness Tuihuang. pharmacological studies indicate that corn have to have a strong diuretic effect, can promote bile secretion, reduce its viscosity and Bil content. polyporus polypores Section for fungal sclerotia of Polyporus umbellatus, sexual ping light sweet, good diuresisʪ; Zexie for Alismataceae Alisma perennial swamp plant tubers, sexual cold sweet talk, good diuresisʪGong,й; II drugs have to help corn Qingre dampness, cholagogic Tuihuang power. sheng yi renof sweet light,ʪdiuresis, and can Qingre Jianpi to strengthen the Huazhuo dampness, as well as drug force Qingre. because of the side for the wet weight of evidence rule hot light, wet forаits viscous nature, are most vulnerable to anesthesia gas machine, air-Jiao Zhizhong impeded, movements disorders, Fangzhong Chenpi therefore also chosen blindly, warm bitter drug Sim, good qi dampness, ChangƢand stomach so that the wet gas line, and the stomach and spleen. ginger, jujube match, to reconcile the spleen and stomach, but also to reconcileζ, make the sauce sweet and delicious.
