With regard to the issue of hepatitis B, we must help me ah!
I was�������morning to check. Eat a few boiled eggs to go.������like to check out there. Blow too much for me, and I do not feel unwell. I have read, like hepatitis B are of particular foods are offensive, but what I like to eat it! And what does not fatigue, nausea, what, everything normal. Why am I so normal individuals have this disease ah ghosts. How can we cure the ah. I do not dare reviewed.
The results help me take a look at ah:
The results of the English abbreviation reference unit
Hepatitis B surface antigen: HBsAg 24.83 (+) 0.0-1.0 S / C. 0
Hepatitis B surface antibody: HBsAb 0.00 (-) 0.0-1.0 S / C. 0
E antigen of hepatitis B: HBeAg 23.70 (+) 0.0-1.0 S / C. 0
Hepatitis B E antibody: HBeAb 56.25 (-) 1.0-999 S / C. 0
Hepatitis B core antibody: HBeAb 0.62 (+) 1.0-999 S / C. 0
Answer:
1, How do I know if infected with hepatitis B?
Please check HBVM is commonly known as hepatitis B, "two pairs of semi-", at present there are "three" and "three pairs of semi-", but in the detection of no real significance on the expansion of the significance of the results are discussed below, but To judge by the best doctors.
2, What are the markers of hepatitis B?
Surface antigen (HBs-Ag), surface antibody (HBs-Ab);
E-antigen (HBe-Ag), E-antibody (HBe-Ab);
Core antibody IgG (HBc-Ab-IgG), the core antibody IgM (HBc-Ab-IgM);
Pre-s protein;
HBV-DNA.
3, HBVM significance?
HBsAg (+) prompted infected with the hepatitis B virus, but can not prompt and infectious viral replication;
Anti-HBs (+) indicated a protective antibodies against hepatitis B immune, injection of hepatitis B vaccine and natural infection can be cured after the production of anti-HBs;
HBeAg (+) is an indicator of hepatitis B virus replication, suggesting that infectious;
Anti-HBe (+), under normal circumstances prompted a low hepatitis B virus replication or reproduction, in some cases, DNA testing combined with the presence of the virus mutates clear;
Anti-HBc-Ab - IgG prompted infected with hepatitis B is the epidemiology of hepatitis B screening;
Anti-HBc-Ab - IgM tips may have hepatitis B immunization-related activities, but the inspection accuracy is not high;
Pre-s1 protein, positive illness prompted to copy;
HBV-DNA, prompted the extent of viral replication;
4, B 5 conventional sort?
(1) surface antigen (HBs-Ag)
(2) surface antibody (HBs-Ab)
(3) E-antigen (HBe-Ag)
(4) E-antibody (HBe-Ab)
(5) core antibody IgG (HBc-Ab-IgG)
This article referred to as hepatitis B, whichever is five sort.
5, hepatitis B combination of five common?
1,3,5-positive, commonly known as������, suggesting that hepatitis B virus infection, infectious;
1,4,5-positive, commonly known as����, suggesting that hepatitis B virus infection, infectious small or none;
2-positive, mostly the result of vaccination; or cured after infection;
2,5-positive, suggesting that recovery after infection (2,4-positive; 2,4,5 positive for the same meaning)
6, a simple 5-positive prompted what?
HBVM that there is a certain concentration, if long-term stable condition, some HBVM concentration will be reduced or even disappear, so that reagents could not be detected, shown as negative,
5 simple tips infected with hepatitis B-positive, there are two possibilities: 2,5 or 1,5-positive-positive, 2 or 1 because the concentration of the lower detection see. Based on current experience, the former are more likely to some.
We know that the 2,5-positive hepatitis B infection after prompt recovery, the body has been established for hepatitis B surface antigen immune mechanism, when the injection of hepatitis B vaccine will stimulate the immune, so that the surface to increase the concentration of antibodies, according to this principle, we can further 5 positive judgments simply a situation to which they belong.
Methods: Injection of a vaccine to stimulate immunity, a month to check, if the surface of antibody to yang, that it was 2,5 positive, otherwise it should be positive 1,5.
Note: The simple 4-positive or 4,5 positive significance with this.
7, liver function, including what?
Liver function test is an important indicator to judge the disease, conventional projects are:
Alanine aminotransferase (ALT), or Valley - pyruvic transaminase (GPT);
Aspartate transaminase (AST), or Valley - grass transaminase (GOT);
Alkaline phosphatase (ALP);
��-glutamyltranspeptidase enzyme (GGT);
Total bile acid;
Albumin / globulin (A / G);
Total bilirubin (T-Bil) and direct bilirubin (D-Bil).
(1), ALT and AST:
ALT and AST are mainly distributed in the liver or liver cells. Necrosis of liver cells when ALT and AST will be increased. Its higher degree of liver cell damage and the degree of consistency, it is the most commonly used indicator of liver function. The two enzymes in the liver cell distribution is different. ALT are mainly distributed in the cytoplasm of liver, AST are mainly distributed in the cytoplasm of liver cells and liver mitochondria. Therefore, different types of hepatitis in patients with elevated ALT and AST levels and AST / ALT ratio is not the same. Acute hepatitis and chronic hepatitis and light, although the damage liver cells, liver cells, mitochondria are still intact, they release into the blood and only exists in the cytoplasm of liver ALT, therefore, is mainly expressed in liver function ALT elevation, the AST / ALT ratio <1. Severe hepatitis and chronic hepatitis medium and heavy, liver cells, mitochondria also have been seriously damaged, AST from the mitochondria and cytosolic release, which showed AST / ALT �� 1. Patients with liver cirrhosis and liver cancer, liver cell damage even worse, mitochondria have also been seriously damaged, so, AST increased significantly, AST / ALT> 1, or> 2. Patients with alcoholic liver disease, AST is often greater than the activity of ALT.
(2), ALP and GGT
Alkaline phosphatase (ALP) and ��-glutamyltranspeptidase enzyme (GGT or ��-GT) is a diagnosis of biliary system diseases commonly used indicators.
Alkaline body exists in almost all organizations, but the bones, teeth, liver, kidney more content. Normal serum alkaline mainly from the bone, resulting from osteoblasts by blood to the liver and excreted from the biliary system. Therefore, cholestatic hepatitis and extrahepatic obstruction significantly increased the enzyme.
��-glutamyltranspeptidase enzyme in the body very broad distribution, such as kidney, liver, pancreas and other organs have this enzyme. However, serum ��-glutamyltranspeptidase enzyme mainly from the liver and therefore has a strong specificity. Hepatobiliary system diseases, this enzymes. When the recovery period when hepatitis, ALT and AST has returned to normal, ��-glutamyltranspeptidase enzyme has not yet dropped to normal. Therefore, at present, often in patients with this enzyme as whether to resume the normal work of the mark. Alcoholic hepatitis and obstructive jaundice patients significantly increased GGT.
(3), albumin / globulin (A / G)
The production of albumin in the liver, liver function impairment serious reduction in albumin to reduce the extent and severity of hepatitis parallel. Chronic and severe hepatitis and cirrhosis in patients with lower serum albumin concentration. Albumin nutritious cells and maintaining the role of osmotic pressure within blood vessels. Albumin decrease, the blood vessels inside the lower osmotic pressure, the patient may appear ascites. Immune globulin is an organ created, when the body of virus antigen (the enemy), the body's immune organs should send more troops to destroy the enemy. Therefore, have increased globulin. Chronic hepatitis and cirrhosis patients have a reduction of albumin, globulin have increased at the same time, resulting in A / G ratio inversion. Serum albumin for the normal 35-50g / L, globulin for 20-30 g / L, A / G ratio of 1.3-2.5.
(4), total bilirubin (T-Bil) and direct bilirubin (D-Bil)
People generally longer life span of red blood cells to 120 days. After the death of red blood cells become indirect bilirubin (I-Bil), by the liver into direct bilirubin (D-Bil), the composition of bile into the bile duct, and finally discharged by the stool. Indirect bilirubin and direct bilirubin is the sum of total bilirubin (T-Bil). Any one of these obstacles can cause jaundice occurred. If too many red blood cell damage, resulting in too much indirect bilirubin, liver can not be totally put it into direct bilirubin, hemolytic jaundice can occur; when the liver cells lesion, or can not be normal because of bilirubin into bile, or swelling due to liver cells, so that the intrahepatic bile duct pressure, obstructed bile excretion, so that blood bilirubin increased, this time on the occurrence of liver cell jaundice; Once extrahepatic biliary system of the tumor or calculus, will biliary obstruction, bile excretion can not be smooth, and the occurrence of obstructive jaundice. Hepatitis patients with jaundice usually jaundice liver cells, which means direct bilirubin and indirect bilirubin were elevated, and cholestatic hepatitis patients mainly to increased direct bilirubin. Total bilirubin of normal for the 1.71-17.1��mol / L (1-10mg / L), direct bilirubin of normal for the 1.71-7��mol / L (1-4mg / L).
8, need to check the liver and gallbladder spleen B-it?
Patients with chronic hepatitis B should be regularly checked Hepatobiliary B-spleen, liver and gall spleen is the imaging examination of chronic hepatitis, cirrhosis, fatty liver, ascites, liver cancer have some tips and diagnostic role.
9, AFP What? What is the significance?
Alpha-fetoprotein (AFP) is in the embryonic period of human blood contains a special protein, the fetus after birth, serum AFP concentration dropped, 1 year fell to normal, normal adult liver cells lose the ability of synthesis of AFP, the serum levels of very Micro (General <20��g / L). HCC can be significantly increased, chronic hepatitis, cirrhosis can AFP molecular variants can also have a transient increase.
10, What is PCR?
PCR polymerase chain reaction name (Polymerase Chain Reaction, PCR), is in vitro nucleic acid amplification technology, could be the target gene or a DNA fragment in a short time doubled to hundreds of thousands and even millions of times, enough amplified DNA Analysis of research and testing for identification.
11, PCR detection of DNA changes in numerical significance?
PCR detection of the DNA double the millions of times, it will expand a lot of results. Clinical results will be twice the control, changes in more than 100 times before that meaningful. For example: 1 * 107, increased to 1 * 109 or lower for 1 * 105 to have any meaning.
Many doctors to change the value of low amplitude to illustrate its efficacy, there is no basis. Even worse, will be testing a single forgery, when each patient medication gradually reducing the value to patients with false hope that the long-term medication, but delayed the treatment of diseases.
12, how to treat viral load testing (DNA)?
Many patients with this value attached, in fact, is a misunderstanding, and many doctors also use this to frighten patients, took the opportunity to sell drugs, should pay special attention to.
From the pathogenesis of hepatitis B can be seen, only the viral replication is not immune response, will not cause liver inflammation, but also hepatitis does not exist. So when the long-term indicators such as liver function normal, and more prompt in stable condition at this time even higher degree of viral replication, nor does it recommend treatment.
