I admitted to the civil service because of fatty liver caused by a transaminase 127 other questions are not
I admitted to the civil service because of fatty liver caused by a transaminase 127 other questions do not have it through a medical examination
Answer:
Lowering transaminase identify the cause is the key
Source: Sohu Health Author:Ա
Long-term liver disease in patients with high transaminase how to do?
Experts point out - accurately identify the causes of transaminase Express to reduce is the key
Yangquan, Shanxi body of Lee two years ago, Richard found elevated transaminase, has been more than the hospital for an examination of the hepatitis indicators checked many times, there is no clear reason, the treatment of intermittent, high transaminases when low volatility than Great. Over the past two years a total of ten thousand-odd spent 4 clinics costs, the overall condition is not stable, 6 months ago, came to the PLA 302 hospital for governance experts for Lee to do a liver puncture examination, diagnosed as autoimmune liver disease, then for Lee has developed to the main immunosuppressant, Baogan Jiangmei supplement the treatment. over the past few months, Lee has always been of aminotransferase to normal, no excessive volatility.
Hebei Cangzhou accounting of one rural Cho, but also for many years transaminase increased governance to governance go, and always did not improve and went to 302 after the hospital, further examination a number of indicators of hepatitis C virus, diagnosed as chronic hepatitis C, experts immediately established him to anti-virus mainly Baogan Jiangmei supplement the treatment. A year later, the basic cure for Hepatitis C Zhao, always maintain normal transaminase.
In fact, in real life there are a considerable number of people over many years of abnormal liver function, the main manifestation is abnormal transaminase repeated, high. Although after treatment, but the effect has always been poor. This is how the same thing? This how to treat the situation? author interviewed in the PLA 302 hospital liver, director of Integrated Traditional and Western Medicine, Chief Physician Dr. Liu Shijing.
Aminotransferase are highզ
Dr. Liu said that the liver function to check the most basic, the most important indicator is the transaminases, usually including serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) 2. GPT mainly in liver cells of the soluble part of Protoplasmic , hepatocellular inflammation disease, caused by cell swelling, necrosis, or increased liver cell membrane permeability, etc., may allow the release of glutamic-pyruvic transaminase in the blood cycle, which increased serum alanine aminotransferase. aspartate aminotransferase mainly in liver mitochondria When the liver necrosis or serious damage can be caused by the aspartate aminotransferase were significantly increased.
According to Dr. Liu, the two transaminase of normal for the following 40 international units, more than 40 international units can be recognized as abnormal liver function. According to the diagnostic criteria of hepatitis, for chronic hepatitis B patients with the severity of the disease can be in accordance with the light, moderate and severe breakdown, if the alanine aminotransferase 40-120 units / L, known as mild hepatitis B; 120-400 GPT units / L, known as the moderate hepatitis B; alanine aminotransferase greater than 400 units or become severe hepatitis. alanine aminotransferase and aspartate aminotransferase in determining the ratio of the size of the extent of disease progression has important significance. Generally speaking, the course of a short, light damage to liver cells in real terms, better prognosis, the pass usually alanine aminotransferase increased significantly , alanine aminotransferase / aspartate aminotransferase ratio greater than 1.5; course of a long, chronic high degree of real damage to liver cells weight, those with poor prognosis, customs usually significantly increased aspartate aminotransferase, alanine aminotransferase / aspartate aminotransferase less than 1.0. Under normal circumstances, the early liver cirrhosis and liver cirrhosis in patients with alanine aminotransferase / aspartate aminotransferase ratio at 1.0 below. transaminase values in patients with chronic hepatitis is always high, reflecting inflammation of liver cells has not stopped, hepatocellular swelling, necrosis of the continued existence .
What are the reasons for the high transaminase
Dr. Liu pointed out that elevated transaminase caused for a variety of reasons, in order to solve the long-term high transaminase problems, we should first find out the reasons for, and then do the right remedy.
Dr. Liu said that the cause of the common causes of elevated transaminase have: the liver disease itself, especially the various types of virus hepatitis, cirrhosis, liver abscess, liver nodules, liver, fatty liver, etc., can cause varying degrees The elevated transaminase. In addition to the liver, the other body tissues such as heart, kidney, lung, brain, testis, muscle also contain this enzyme, so when myocarditis, pyelonephritis, Lobar Pneumonia, tuberculosis, hepatitis B encephalitis, polymyositis, acute sepsis, intestinal typhoid, meningitis, malaria, cholecystitis, leptospirosis, influenza, measles, schistosomiasis, such as crush syndrome, also can be elevated transaminase Antiaris Medium. Since transaminase excretion from the bile duct, and therefore if there is bile duct, gallbladder and pancreatic diseases, bile duct obstruction, but also enables increased transaminase. drug-induced liver injury or poisoning, as well as drug allergy can cause elevated transaminase, and often with cholestatic jaundice and liver cell injury. normal pregnancy, gestosis, acute fatty liver of pregnancy are also common causes of elevated transaminase. In addition, after intense exercise can also be caused by elevated transaminase. chronic elevated transaminases are clinical diagnosis of a special temporary, but also a lot of non-viral hepatitis, liver disease only in patients with clinical manifestations, most through history, physical examination and a series of tests to determine liver pathogen; but there is still abnormal liver function can not be part of routine examination be interpreted, which requires further study to do liver biopsies inspection, thoroughly understand the cause. only to understand the causes of elevated transaminase caused by the above are of which can be done to get back the right remedy.
Dr. Liu pointed out that patients with elevated aminotransferase after repeated treatment, if the effect of poor, in addition to considering the above objective reasons, but also look for subjective reasons - the treatment of inappropriate or incomplete questions. Transaminase is a repeatedly elevated symptoms and manifestations, if treatment is considered only Baogan Jiangmei, while ignoring the fundamental treatment of disease, it is only the symptoms, regardless of cause, treatment resulted in "the cart before the horse", will naturally not a very good effect. For example, chronic hepatitis B caused by high transaminase, and its never-ending source of trouble lies in hepatitis B virus replication, immune mechanism disorder. Therefore, Dr. Liu stressed that the treatment of hepatitis B transaminase increased to "two-pronged approach", "NPC", if only the use of lower enzyme drugs, treating the symptoms rather than cure, transaminase can be temporarily controlled, but once the discontinuation, transaminase often increased again, this "rebound" phenomenon is extremely common in clinical; in order to ensure the thorough control of hepatitis B disease, we must first antiviral treatment, suppression and eradication of hepatitis B virus is a fundamental measure is only an expedient measure only Baogan Jiangmei. there are a considerable number of patients despite long-term treatment, but always abnormal transaminase, which some patients are not choosing the right main and effective JiangMei drugs, appears to many types of drug use, but do not belong to Baogan Jiangmei effective drugs, governance to governance go, do not bear fruit. Therefore, this part of patients, the selection effective, the role of durable power of liver JiangMei essential drugs.
How the treatment of high transaminase
Dr. Liu reminded, at present, a variety of liver JiangMei a wide range of drugs, and truly effective Baogan Jiangmei medication are few in number, in the course of treatment must not abuse, we must find the real cause elevated transaminase reasons, for this the reasons for treatment in order to obtain good results. Dr. Liu suggested that patients in the course of treatment and medication to follow the following three principles:
First, select the correct and effective Baogan Jiangmei Drug. Treatment of various etiology caused by elevated transaminase, effective drugs are the main active ingredients of Chinese medicine and its extracts, containing the general selection schisandrin C, glycyrrhizic acid, oleanolic acid, silymarin and other chemical ingredients. Liuwei Tablets five are from Schisandra, licorice, Phillyrin drugs such as composition, with Yigan Zishen, Jiedu Qushi efficacy for the treatment of a variety of chronic hepatitis were elevated transaminase , is a new generation of Baogan Jiangmei drug treatment has been widely used in clinical. as long as the proper use of the above patients JiangMei drugs, transaminase can be effectively controlled, and JiangMei treatment lasting stability.
Second, the treatment must be guaranteed. When Jiangmei drug so transaminase returned to normal, should gradually be reduced JiangMei drug dosage, avoid sudden discontinuation of treatment. JiangMei drug use at the course of treatment should be more than 1 year, even if liver function are often complex will also need to maintain at a minimum level of consolidation treatment. For example, the use of intravenous drip Ganlixin Jiangmei, normal liver function can be replaced by daily fluid infusion on alternate days, followed by every other loser on the 2nd time; if the switch to oral substitutes Jiangmei when the best selection of potent drugs such as tablets, etc. Liuwei Friday, the smooth passage of the transfer of oral infusion changed to conversion.
Third, at the same time Baogan Jiangmei, the target must be the cause of "radical" measures. For example, the treatment of hepatitis B must be anti-viral and immune therapy adjust. The treatment of hepatitis B is a world problem, the current best approach is to combined in a comprehensive way, that is, the so-called "NPC", anti-viral treatment for the cure of law, for the treatment of the root. Hepatitis B treatment although there were no effects of drugs available, but there are some effective drugs, the representative of the latest research the results of drugs are nucleoside anti-viral drugs - adefovir, entecavir, telbivudine and so on, a long-term interferon treatment of hepatitis B is currently one of the main drug. Jiangmei hepatitis B patients in the treatment of liver at the same time, with the necessary anti-virus treatment. after a long-term effective treatment of patients with laboratory examination, hepatitis B virus replication indicators all negative, hepatitis B virus e antigen, e antibody study between serum conversion, which means that the disease was fundamental improvement in transaminase long will it be possible to obtain stability. the treatment of hepatitis C, first of all consider the use of interferon combined with ribavirin antiviral therapy, while United Baogan Jiangmei drugs Tablets Liuwei five and so on, course of treatment at more than 1 year . necessary in patients with autoimmune hepatitis using immunosuppressive agents simultaneously five United Liuwei Tablets such as liver Jiangmei drugs, treatment time is also more than 1 year. for alcohol liver disease, fatty liver, such as, first of all necessary alcohol, improving diet, lose weight At the same time, selected five Liuwei Tablets Jiangmei drugs, such as the liver. In short, in order to solve this problem transaminase is always high, we must understand the reasons, to prescribe the right medicine to bear fruit.
