What should be the early cirrhosis drug treatment?
I have hepatitis B virus has been years, now 34 years old, used to eat raw fish, the existing liver fluke eggs. This is a typical two-month liver palms, telangiectasia neck has emerged brandy nose. Eyes recurrent pain, hands and chest has appeared in several spider, sexual desire is getting worse, discolored hair, bath recurrent congestive red eyes, frequent nausea, constipation, diarrhea, abdominal inflation, anorexia and fatigue, dry mouth and tongue dry, thinten, liver discomfort. last year, also suffering from duodenal ulcer-yang, special last winter itch.
Is to check:
Liver function albumin 42,
MG 30,
White / ball ratio of 1.4,
Direct bilirubin 2.3,
Indirect bilirubin 5.3, the other normal.
Quantitative detection of the virus at the scope (February to March this year, quantitative virus 2.6 * 10 four square, normal liver function, B-points of light than coarse Micronesia)
Ganxian four hyaluronic acid (HA) 232,
Human type III collagen 146,
Routine inspection, coefficient of variation of red blood cell distribution width (RDW-CV) H 15.1%,
B-ultrasound findings
Liver: left lobe liver length 79mm, thickness to diameter 54mm, right lobe oblique diameter 121mm, portal vein diameter of 10mm, common bile duct diameter of 3mm, and normal liver morphology, rough spot, echo distribution, blood vessels running clear, intrahepatic bile duct non-expansion , bile duct wall structure revealed. cholecystectomy: gallbladder length 56mm, width 21mm, gallbladder morphologically normal, smooth-walled, with transaudient good.
Spleen: spleen diameter thick door 35, splenic vein diameter 6, spleen normal morphology, capsule integrity, and splenic echo homogeneous substance.
Pancreas: head diameter of 13, body diameter 15, the end of Path 15, normal pancreas morphology, capsule integrity, echo uniform, not the expansion of pancreatic duct.
Diagnosis: (1) intrahepatic rough spot. (2), gall bladder, spleen, pancreas without abnormal images.
CT examination:
Liver size, shape and normal, intrahepatic uniform density, no focal abnormal density, intrahepatic vascular Traveling normal liver outside the bile duct without expansion, not the spleen, gallbladder small size of pancreatic morphology and density of normal, no retroperitoneal swollen lymph nodes. Diagnosis: liver, gallbladder, spleen, pancreas no obvious abnormalities. (The above inspections are to do at the Guangzhou Nanfang Hospital)
I would like to ask, my liver palms and spider increasingly obvious and increasingly weak, eyes more and more pain, sexual desire is getting worse, is not more serious liver disease? Me this liver disease is liver fibrosis, or early cirrhosis or inflammation Events startled? my liver palms and spider are becoming increasingly clear not have relations with the liver fluke eggs? If you have liver fibrosis or early cirrhosis What should be the drug treatment? Security Network Fiber pills, Compound Danshen Dropping Pill, glycyrrhizin tablets required simultaneously with it? prolonged use will greatly damage the liver? efficacy prescribed obvious? I used to drink, and drug treatment of sexually transmitted diseases have a year of liver Is there any damage? I need to check other causes of liver disease? Afraid to do my liver biopsy, what I now have this condition there is no need to do liver biopsy? Thank you!
Answer:
Cirrhosis
References:
About the disease:
Cirrhosis refers to one or more of the reasons for the long-term or repeated damage to the liver, resulting in extensive damage to liver parenchyma, hepatocellular necrosis, fibrous tissue hyperplasia, normal structure of liver disorders, texture hardens. May be complicated by splenomegaly, ascites, edema , jaundice, esophageal varices, bleeding, hepatic coma.
Health Guide:
1. Actively prevent: cirrhosis are caused by different substantive liver degeneration and progressive development of a consequence.
Emphasis on prevention and treatment of a variety of primary disease, active prevention and treatment of chronic hepatitis, schistosomiasis, gastrointestinal tract infections, and application to avoid contact with toxic substances on the liver to reduce the pathogenic factors.
2. Emotional stability: the liver and the spirit of emotion is a very close relationship. Poor emotional, mental depression, rage emotion may affect liver function and accelerate the development of lesions. Establish a strong will, feeling cheerful, and pull themselves together to eliminate the burden of thought, will be beneficial to improve the condition.
Three. Static and dynamic binding: decompensated cirrhosis dysfunction, complicated by ascites or infection should be an absolute bed rest. At full compensatory function, condition stable job could be done as easily or appropriate activities, beneficial physical exercise, such as walking, to do, Taijiquan, Qigong, etc.. active in order to not feel for the degree of fatigue.
Iv. Use simple: too much blind general abuse of drugs, will add to the burden of the liver is not conducive to the restoration of the liver. On the liver of harmful drugs such as isoniazid, barbiturates should be used with caution or.
Friday.ɾquit: alcohol will be able to help fire the blood moving, long-term alcohol consumption, especially alcohol, can lead to alcoholic cirrhosis. Therefore, alcohol can aggravate their condition in patients with liver cirrhosis, and easily lead to bleeding. Long-term smoking is not conducive to the stability and the restoration of liver disease can accelerate the process of cirrhosis, the risk of liver cancer have trigger.
VI. Nursing diet: low fat, high protein, high vitamins and easy to digest diet is appropriate. Do from time to time, quantitative restraint. Early can eat more soy products, fruits, fresh vegetables, proper eating sugar, eggs, fish category, lean meat; when significantly decreased liver function and hepatic coma has threatened, the appropriate response to protein intake control, the promotion of low-salt diet or anti-salt diet. daily salt intake is not more than 11.5 grams, water volume in 2000 milliliters , the severe ascites, the salt intake should be controlled at 500 mg or less, water intake at less than 1000 milliliters. should avoid spicy and hard goods to stimulate the cold food, not eating food in order to prevent overheating hemorrhage.
Cirrhosis of liver damage due to a variety of factors such as chronic active hepatitis, chronic alcoholism, long-term damage to the liver caused by chronic progressive liver disease. To loss of appetite, fatigue, gum bleeding, liver palms, spider, jaundice, white protein low, splenomegaly, abdominal varices, esophageal varices, ascites, etc. as the main performance. late often gastrointestinal bleeding, hepatic coma, severe complications such as secondary infection. cirrhotic patients is of primary liver cancer in high-risk targets, should pay attention to regular checks.
Cirrhosis can be applied to Chinese and Western medical treatment, have a certain effect.
Prescription
1. Cirrhotic patients should pay attention to rest, avoid strenuous exercise; to maintain positive emotions and confidence in conquering the disease.
2. The food should be digestible, nutritious. High-protein, high-sugar, high in vitamins, low-fat diet for patients with liver cirrhosis selection principle.
3. Ascites should have bed rest, increasing nutrition, and to limit salt intake, preferably salt-free or low-salt diet, the daily amount of salt to not more than 5 grams (1 money) is better.
4. Ascites obvious when they restricted water intake, the general into the water, to control daily at 1000 milliliters (equivalent to hospital with salt water bottles 2 bottles). Severe hyponatremia, and should be limited to less than 500 milliliters.
5. Accompanied by esophageal varices, and should refrain from provocative and hard food, so as not to damage the esophageal varicose vein caused by massive hemorrhage.
6. Hepatic coma may have, we should limit the intake of protein, three meals a day should be vegetables.
7. Temperance to quit smoking, do not abuse "Hugan" drugs.
8. Should periodically go to the hospital for liver function, alpha-fetoprotein, ultrasound examination.
Zhang had many years ago, chronic hepatitis, with effect from April last year, are general malaise, marked weakness, right upper quadrant pain Ministry, after a medical examination does governance as "chronic hepatitis, liver cirrhosis," Doctorhim visions adequate intake of high-quality animal protein, to ensure the nutritional needs of the body. sick because of lack of knowledge of disease and does not pay attention to, at the same time, over exertion, which recently appeared in abnormal behavior, answer unclear, slow thinking, such as hepatic coma pre-performance, low-protein feeding, needs to be changed, or even ban protein food, the patient's family this indecisive. the suspicion is that people have to understand that should know and grasp common sense. Speaking of viral hepatitis B, everyone will not be unfamiliar to you. sick - Dan after hepatitis is not well received rest and nutrition, led to further damage to liver cells, cells degeneration and necrosis, fibrous tissue hyperplasia, with the passage of time led to the gradual destruction of liver tissue structure and texture hardens, the performance of light who have loss of appetite, tired of greasy, bloating, fatigue, liver District does not apply. will re-emergence of ascites, digestion, detoxification, coagulation dysfunction, such as liver dysfunction, and symptoms such as portal hypertension. It should be noted that early liver cirrhosis should be noted at rest, a fitting complement to high-quality protein, this is conducive to liver cell repair. If liver cell damage increase, it is bound to be significantly decreased the liver detoxification function, excessive protein intake at this time, but more harm than good, so that the body produce too much ammonia, blood ammonia concentration of ammonia increased savings, resulting in hepatic coma happen. result Early hepatic coma sick tendencies, we must strictly control the intake of animal protein. To avoid negative nitrogen balance, you can add beans ammoniagenes less vegetable protein. Despite the use of ammonia lowering blood ammonia decreased after drug treatment (normal range 37-81mmol / L), also should not add too quickly or too much animal protein, should add fresh vegetables and fruits, to ensure the supply of carbohydrates, moderate fat intake restricted. In addition, patients with liver cirrhosis should also strictly comply with the following points: 1 strict temperance, alcohol can increase the severity of liver cell damage, is not conducive to liver cell repair. II, peacetime stubby food should be avoided, such as bone, barbed-type, hard fruit to prevent injury has been the esophagus and gastric varicose vein rupture hemorrhage. Three, there has ascites, edema patients should use low-salt diet, a daily salt perturbation of less than 2 grams. iv, liver cirrhosis patients in order to maintain patency of faeces, such as constipation Lun, the edible oil, honey, etc. to reduce the accumulation of ammonia to prevent hepatic coma. Friday,ʳ, this is conducive to the liver rest, reducing the burden of liver.
Managers think of ascites due to cirrhosis of the hospital treatment, the majority of liver function recovery, hypoproteinemia may be corrected, the liver to improve internal circulation. Kidney filtration rate increased, ascites disappeared. However, the recurrence rate of ascites due to cirrhosis is very high, and the treatment of the more to the more difficult. Therefore, the prevention of relapse after discharge is essential.
Diet in patients with liver cirrhosis secondary aldosteronism exist, to reduce urinary sodium excretion, renal distal convoluted tubule sodium retention impoundment strengthened, high-salt diet further increased serum sodium levels, can induce ascites. At the same time, barriers to protein synthesis in patients with liver cirrhosis , albumin decreased, if prolonged low-protein diet may increase the hypoproteinemia, ascites recurrence; but eating a large number of mining such as high protein, high fat diet, then add to the burden of the liver to promote health to deteriorate. esophageal exist many patients with liver cirrhosis varicosis, eating coarse food may have varicose vein puncture. happened upper gastrointestinal bleeding. Therefore, emphasis should be placed on low-salt, moderate protein, low-fat diet; eat vitamin-rich food, selection of soft easy to digest food; avoid overeating to avoid hunger, elimination of tobacco and alcohol, pay attention to food hygiene to prevent diarrhea.
Rest day to ensure that more than eight hours of sleep time, avoid fatigue, a gradual increase in the volume of activities, from rest to half-day job day job as well as the whole transition. Enhance immune function to use to promote the regeneration of Chinese and Western medicine, combining movement, take part in physical exercise; maintain ease of mind to avoid the sadness, take part in cultural and recreational activities to enhance physical fitness, improve body resistance to disease, and promote the restoration of liver function and liver regeneration. the prevention of infection in patients with liver cirrhosis low resistance, high-risk peritoneal and other infections. but also in patients with liver cirrhosis where we have ascites infections or other infections exist. were treated and control, no control, such as thorough, or re-infection Reburning infection, so that the resulting ascites. so, contagious disease should be avoided in patients with cirrhosis, the prevalence of infectious diseases as much as possible during the not in public places. the event of infection, should be early and thorough governance.
Avoid the use of common drugsliver damage liver damage has more than 200 kinds of drugs, such as tetracycline, can be fun Sim, antimony agents, arsenic trioxide, chlorpromazine, barbiturates, urethane, azathioprine, isoniazid, para-aminobenzoic salicylic acid, chloral hydrate, chloramphenicol, erythromycin, etc. should be disabled or used with caution. prevention of complications in patients with cirrhotic ascites complicated with upper gastrointestinal bleeding easily, hepatic encephalopathy, kidney disease, ulcer disease, blood disease, diarrhea, electrolyte imbalance, etc., it is necessary to active treatment and minimize damage to the liver.
How the early detection and treatment of cirrhosis of popular science journal of medicine, "seek medical treatment -" Author: Tom Xinguo
China is a hepatitis B virus infection and hepatitis B in areas of high. From viral-induced cirrhosis the most common, are one of the major post-hepatitis B cirrhosis. In foreign countries, especially Europe and the United States with alcoholism alcohol-induced cirrhosis the most common.
General adult suffering from hepatitis B patients through the rest, proper nutrition, support of Chinese and Western medicine treatment of liver, 90% can be cured, only 10% of the patients into chronic hepatitis. Of the 10% of chronic hepatitis, of which 20% may develop into liver cirrhosis, about 1% of the development of liver cancer. so after suffering from hepatitis B, the vast majority can be healed. Therefore, do not have to tension and panic.
The development of liver cirrhosis from viral hepatitis of time can be shorter or longer periods. Long subject to lengthy process in 2030, short of just a few months. Therefore, patients are advised to do a good job of self-care, the attention of convalescence, the maintenance of good life may be greatly affected.
Chronic hepatitis after liver fibrosis, liver cirrhosis can develop.
How to detect early liver cirrhosis?
Early clinical manifestations of liver cirrhosis was not obvious, can be asymptomatic or only mild symptoms such as fatigue, poor appetite, dyspepsia, nausea, vomiting, right upper quadrant pain, diarrhea and so on. These symptoms without the characteristic, general gastrointestinal disease were may appear, is not unique to early liver cirrhosis, so difficult to simply relying on the early detection of symptoms. At physical examination early cirrhosis, the liver often swollen, and some patients with splenomegaly, spider angioma and liver palms can be seen. many liver function tests at the normal range or mildly abnormal proteins are more prominent changes, such as reduced albumin, globulin elevated, white, globulin ratio close to or even inverted.
Well, what other tests can be found so early cirrhosis?
1. Are the best indicators of gold give patients a liver puncture biopsy histological examination. The use of one-second puncture, to take the small amount of liver tissue under the microscope to check to find out whether liver fibrosis and connective tissue formation.
2. To do B-ultrasonography. In the early cirrhosis may be found hepatomegaly, liver echo showed increased thickening. Once developed to a late widened portal vein diameter greater than 13 millimeters, splenic vein widened more than 8 millimeters, spleen by thick, liver reduced liver surface is not smooth, uneven, often accompanied by ascites have.
3. 4 checking blood serum fibrosis. Hyaluronic acid (HA), laminin (LN), procollagen type (P P), collagen (C ). One of 23 has significantly increased, could be considered early cirrhosis.
Early treatment of liver cirrhosis
1. Give due attention to avoid over exertion to rest, can take part in the work of ordinary light.
2. Catering to high-calorie, high protein diet mainly eat vitamin-rich (fresh vegetables and fruits) and digestible food, Do not eat solid food and the rough, a taboo to drink, do not use drugs damage the liver.
3. Drug treatment at a specialist under the guidance of the liver using the protection of Chinese and Western medical treatment in order to improve liver function. Application of anti-fibrosis treatment, such as Kangxian pills, compound Fufangbiejiaruanganpian, -interferon, have anti-fibrosis role. if the hepatitis B virus replication in patients with positive indicators (such as HBV-DNA positive, HBeAg positive) can be applied Heptodin nucleoside antiviral drugs (Lamivudine D). However, avoid too much medication, or else will add to liver burden on the restoration of the adverse liver disease.
In short, we will strive for early cirrhosis early detection, early treatment. When liver disease is still in the fibrosis stage, through active treatment, the disease can be reversed, it is possible to recover. If the disease has progressed to cirrhosis, while treatment can only fight for ease. If the disease has developed to advanced cirrhosis, patients with some complications such as regular hepatic encephalopathy (hepatic coma), upper gastrointestinal bleeding, ascites, hepatorenal syndrome, infection, etc., then a poor prognosis.
What is cirrhosis?
Are a variety of reasons cirrhosis of the liver caused by chronic, progressive diffuse change. Its characteristics are a cause of or more of the causes of repeated, long-term injury of liver cells, resulting in liver cell degeneration and necrosis. Extensive degeneration and necrosis of liver cells after , intrahepatic connective tissue regeneration, appear diffuse fibrous tissue hyperplasia. intrahepatic liver regeneration at the same time, the formation of regeneration nodules, the normal structure and angiogenesisСҶdestroyed, the formation of false lobules. After a fairly long period of time (a few years or even decades), the liver gradually happen deformation, texture hardens, clinically called the physiological and pathological changes in liver cirrhosis.
Cirrhosis are more common in our country, the majority of liver cirrhosis, for a small number of alcohol-induced cirrhosis of the liver and cirrhosis of Schistosoma. Because of early liver cirrhosis after the positive control, can be reversed or is no longer made, but will have a serious impact in patients with advanced quality of life, even life-threatening, so prevention and treatment of liver cirrhosis is very important.
Caused by cirrhosis of the reasons for which?
Cause of cirrhosis can be divided into the following 8 categories:
(1) hepatitis C virus: The most common are hepatitis B virus, hepatitis C virus and hepatitis D virus infection. Hepatitis B virus infection in people who have some chronic hepatitis, and chronic hepatitis B and a small number of the development of liver cirrhosis. about half of acute hepatitis C develop chronic hepatitis, one of 10% 30% will happen cirrhosis. dependent on hepatitis D virus Hepatitis B virus can happen, some patients develop liver cirrhosis.
(2) alcohol factors: long-term alcohol consumption resulted in substantial damage to liver cells, the occurrence of fatty degeneration, necrosis, liver fibrosis, cirrhosis occurred in severe cases.
(3) cholestasis: a long-term chronic cholestasis, causing liver cell inflammation and ductular reaction, and even necrosis, the formation of biliary cirrhosis.
(4) congestion factors: long-term repeated chronic cardiac insufficiency, constrictive pericarditis and hepatic vein occlusion can cause liver congestion, lack of oxygen so that hepatocytes necrosis, degeneration and finally cirrhosis. Because one of the heart caused by cirrhosis Heart-induced cirrhosis.
(5) drug-induced or chemical toxicology factors: long-term use of certain drugs, such as dual-vinegar phenol Ting, Xin can be fun, such as methyl-dopa can lead to drug-induced hepatitis, and finally the development of liver cirrhosis. Long-term exposure to certain chemical toxins, such as four chloride, carbon, arsenic, phosphorus can cause toxic hepatitis, the development of liver cirrhosis.
(6) metabolic disorders: Copper metabolism disorders, seen in hepatolenticular degeneration. Iron metabolism disorders, seen in hemophilia, galactosemia, cystic fibrosis disease, -antitrypsin deficiency, glycogen storage disease, Tyrosine metabolism disorder, hereditary hemorrhagic telangiectasia, the above metabolic and genetic defects can lead to cirrhosis.
(7) parasitic infections: Schistosoma infection found in South China, could lead to schistosomiasis, caused further lead to cirrhosis of liver fibrosis. Human Clonorchis sinensis infection after treatment can occur promptly cirrhosis.
(8) other factors: a high degree of malnutrition can be caused by liver cirrhosis, there are a small number of unexplained liver cirrhosis.
How to diagnose liver cirrhosis?
Typical symptoms in patients with liver cirrhosis diagnosed easily, but some patients without typical clinical symptoms, in the occult decompensated, has confirmed it will be difficult at this time. Therefore, the diagnosis of liver cirrhosis is a comprehensive diagnosis.
(1) have viral hepatitis, long-term alcoholics, long-term malnutrition, schistosomiasis or chemical poisoning, such as history.
(2) symptoms: early (compensatory phase) have loss of appetite, ascites, nausea, diarrhea, mild liver and spleen enlargement, vascular nevi, late (decompensated phase) has ascites, bleeding tendency, jaundice, liver palms, splenomegaly, liver, such as volume shrinking.
(3) Liver function test: decompensated liver function and normal or mildly abnormal liver function decompensated apparent anomaly, lower plasma albumin, globulin increased, the proportion of inversion, protein electrophoresis -globulin increased significantly.
(4) Hemogram inspection: Hypersplenism leukocytes and platelets were reduced, severe pancytopenia.
(5), esophageal endoscopy or barium permeability, have esophageal or gastric varices.
(6) B-ultrasonography: changes in liver size, surface and shape, echo changes, the portal vein, splenic vein thickening, and ascites fluid of the dark zone can be seen, spleen size increased.
(7) Liver histology: fiber has the following form and a small nodular or mixed nodular hyperplasia can be diagnosed.
Chronic hepatitis and liver cirrhosis What is the difference?
Chronic hepatitis as the main pathological changes in liver cell necrosis after stent mesh fiber structure collapse, the formation of fibrous scar. The other is the regeneration, the formation of concentric size nodules. Elements of the clinical diagnosis of chronic hepatitis, with the exception of history at one year we can take reference from top to bottom, should have the following conditions: regular or recurring symptoms, general health decline significantly diminish the ability to work. hepatomegaly, quality degree of hardness in the middle above, may have tenderness, has accompanied by splenomegaly of. number of spider and liver palms, at diagnosis has a certain sense. positive chronic liver damage, in particular albumin and globulin ratio has changed.
Clinical practice can be divided into: chronic active hepatitis: the digestive tract has obvious symptoms (loss of appetite, bloating, diarrhea), and generalized weakness. Activities to the deterioration of symptoms, jaundice slow increase, have liver pain, occasional right upper quadrant pain . and have hepatomegaly with tenderness. transaminase, turbidity, such as musk deer liver function tests positive change in varying degrees. chronic non-active hepatitis: Symptoms generally small, does not deteriorate after the symptoms, sometimes fatigue, poor appetite, occasional right upper quadrant mayflu, many non-tender hepatomegaly, liver function is normal scope of many.
The main clinical manifestations of liver cirrhosis for the liver, splenomegaly, splenomegaly is extremely common. But to rule out the possibility of splenomegaly caused by diseases such as malaria, leishmaniasis and schistosomiasis, and so on. Splenomegaly at diagnosis has a certain sense. Application X-ray examination of esophageal or gastric varices whether, in determining the diagnosis of liver cirrhosis extremely valuable. general from the history, signs, liver function tests and differential diagnosis of chronic hepatitis is not difficult, phthalocyanine tetrabromo phenol sodium (BSP) test will be very helpful, ultrasound examination may assist diagnosis, liver biopsy can be diagnosed with chronic hepatitis or cirrhosis, but must strictly control their indications.
Pathological characteristics of liver cirrhosis and classification are what?
Cirrhosis (Liver Cirrhosis) are caused by a variety of causes of chronic liver disease. Are characterized by repeated liver cells chronic degeneration and necrosis, followed by fibrous tissue hyperplasia and nodular regeneration of liver cells, so that the normal lobular structure of liver damage and blood circulation pathways changes in the liver caused by deformation, narrow, harden and cause the formation of nodular cirrhosis. Early no obvious symptoms, the latter appeared in varying degrees of portal hypertension and liver dysfunction performance.
The classification of liver cirrhosis complicated and diverse, and some classification by etiology, and some by disease classification, each with its own advantages and disadvantages. At present, liver disease according to international studies in general (IASL) classification, according to etiology are divided into viral hepatitis, and alcoholic , bile, and occult cirrhosis; by lesions were divided into small nodular, large nodular type, size, nodular mixed type and incomplete septal cirrhosis. domestic often combined etiology, clinical manifestations of disease and the integrated classification, sub - for the portal vein of (equivalent to small nodular type), after necrosis of (equivalent to large nodular type and size of nodular mixed type), bile, and stasis, and parasites and pigment cirrhosis. are the most common door cirrhosis vein, followed by post-necrotic liver cirrhosis and biliary cirrhosis.
Liver cirrhosis in several clinical phase?
Clinically divided into cirrhosis and decompensated cirrhosis period. Decompensated also known as misprision of a view can be asymptomatic, routine liver function tests normal. When there are clinical symptoms, has entered the period of decompensation, the principal has fatigue, weakness, satisfied minus, abdominal swelling, two pain, significantly decreased liver function, enlargement of the liver often narrow, and the emergence of ascites, edema, jaundice, fever and so on. decompensated cirrhosis clinical manifestations can be summarized into two syndrome, that is, from liver dysfunction and portal hypertension caused by.
What is early cirrhosis, its clinical manifestations are what?
Means of early liver cirrhosis without any specific clinical symptoms or signs, liver function tests no obvious abnormalities, but in liver histology, there are obvious pathological changes. Research have confirmed that patients with early liver cirrhosis, intrahepatic the species have increased collagen content, to one of type , collagen deposition mainly increased. advanced cirrhosis mainly to an increase in type , type dominated early, with the progress of liver fibrosis, / type I collagen ratio from 1 to 1.59, -type collagen fibers increased, participation in the formation of connective tissue, and its reversibility, and were seen primarily in the late liver cirrhosis.
Because of early liver cirrhosis in clinical practice without any specific symptoms and signs, there are sub-clinical stage of the pathological changes, but some patients can have the following performance.
(1) systemic symptoms: mainly weak, easy fatigue, physical decline. A small number of patients facial pigmentation can occur.
(2) chronic dyspeptic symptoms: Fresh satisfied receded, with abdominal distension or constipation, diarrhea or liver pain, tiredness after the obvious.
(3) signs: a small number of patients can be seen spider, mild to moderate swelling of the liver, was particularly prevalent in the alcoholic cirrhosis patients, generally without tenderness. Spleen may be normal or mildly swollen.
Clinical manifestations of the above easily and often confused with the original or chronic liver disease patients do not give rise to attention.
Respondents: olive1109 - Senior Manager 6 2-21 17:54
The other answer a total of 2
cirrhosis therapeutic principles:
(1) a reasonable application of the protein. Liver protein synthesis are a venue for a day by 1114 grams of liver albumin synthesis. When the liver cirrhosis, the liver can not be a good synthesis of the protein. Necessary and reasonable arrangements at this time on the protein intake to prevent the occurrence of hepatic encephalopathy. can choose from a variety of sources of protein food. in order to enable patients to better adapt to, you can eat to casein-based diet, to put the right amount of cheese-doped chicken, fish, lean meat, eggs every day have a little protein to balance the diet.
(2) supply the right amount of fat. Some patients suffering from liver cirrhosis, the fear of eating fat, in fact, fat should not be too restrictive. Due to cirrhosis of pancreatic insufficiency, bile secretion decreased hilar lymphatic or have other reasons congestive near half of the patients with fatty liver cirrhosis dysentery, malabsorption of fat. When the above symptoms should be controlled fat. However, if patients without such symptoms, and can adapt to dietary fat, in order to increase the calories, fat is not easy too restrictive . If biliary cirrhosis using a low-fat, low cholesterol diet.
(3) an adequate supply of carbohydrates. Carbohydrate the body can fully adequate glycogen reserves to prevent the toxin on the liver cell damage, a day to eat starchy foods 350 grams 450 grams.
(4) restricted diet of water and sodium. When there is edema, or mild ascites of patients should be given to low-salt diet, daily intake of salt is not more than 3 grams; serious edema when suitable salt-free diet, sodium should be limited at about 500 mg. fasting more sodium foods, such as steamed buns, when not to use the base, can be used fresh yeast, or to eat salt-free bread. vermicelli in more sodium and should not eat. Second, a variety of pickles and pickles are also very many sodium, in patients with liver cirrhosis should be the absolute limit. condiment simultaneously to sodium glutamate in monosodium glutamate-based, will add to the liver on the burden of water and sodium metabolism. Now, the market to facilitate all types of customers, but also supply the low-sodium, low sodium soy sauce and salt-free soy sauce. At the time of cooking dishes, paying particular attention to cooking methods, or instead increase the sodium intake, for example, someone in to do fish, meat, when used in salt or soy sauce soaked first, then and then washed the surface of salt water, although it is not salty to eat, but too much sodium has been far from the excess. to do all kinds of dishes, the first non-salt or soy sauce, when the last salt Cookor soy sauce, then putor vinegar, soy sauce, salt to eat. This not only taste, but also limited sodium intake. other high sodium foods such as seafood, ham, egg, dried meat floss, also should be strictly controlled. daily into the water should be limited to 1000 milliliters 1500 milliliters.
(5) Eat more zinc, magnesium-rich food. Cirrhotic patients generally lower level of serum zinc, urinary zinc excretion increased, liver cells also reduced the amount of zinc, when drinking, the blood will continue to reduce the amount of zinc should be strictly forbidden to drink, appropriate to eat lean pork, beef, eggs, fish, such as the amount of zinc more food. in order to prevent the lack of magnesium ions, such as eating many green leafy vegetables, peas, dairy products and cereals and other food .
(6) Vitamin C. Vitamin C directly involved in liver metabolism, and promote the formation of liver glycogen. To increase the concentration of vitamin C, can protect the liver cell resistance and the promotion of liver regeneration. Ascites in vitamin C concentrations and blood levels of the same, Therefore, in ascites should add a large number of vitamin C. peeling should be eating fruit or drinking juice into juice.
(7) diet appropriate light, soft, easy to digest, no stimulation,. Cirrhotic patients often loss of appetite, should be given to the absorption of digestible food,, eat soft food and no stimulation of food, work to fine - to avoid the hard rough food, such as fried foods, nuts, food. esophageal varices when combined, they should pay attention to is strictly prohibited to eat fried food and nuts and dried fruit products, because such food may be punctured esophagus veins, caused by upper gastrointestinal bleeding, resulting in life-threatening. cirrhotic patients must not meet the taste of the happy moment and psychological needs, and the loss of valuable lives.
cirrhosis of food selection
(1) milk, eggs, fish, lean meat, soy products such as high quality protein foods, should be at the daily rotation of the supply of meals.
(2) may be an appropriate choice of glucose, sucrose, honey, fruit juices, such as easy to digest single-and double sugars, to increase the liver glycogen reserves.
(3) parent enzyme rich B vitamins, should pay attention to the supply.
(4) anti-alcohol and all the spicy and pungent food.
(5) Avoid fried foods and do the hardware.
(6) eat less or eat more fiber food and gas production of many foods, such as celery, leek, bean sprouts, sweet potato, dried beans, soft drinks, such as radish.
recipes, for example liver cirrhosis day
Breakfast: Large congee (rice, 50 grams), bread (75 grams of flour), dried meat floss (15 grams of pork Song)
Snacks: sweet milk (fresh milk 250 grams, 10 grams sugar), apple 150 grams
Lunch: Large rice (rice, 150 grams), burning hairtail (hairtail 200 grams),سoilseed rape (Brassica napus 150 grams)
Snacks: red lotus root starch (lotus root starch 30 grams, sugar 10 grams)
Dinner: rice (150 grams of rice), chicken pieces (100 grams chicken), tomatoes fried tofu (bean curd 50 grams, 100 grams tomatoes)
25 grams of oil throughout the day.
Recipe containing more than 2422 kcal energy (10120 kJ).
Dietary Therapy of liver cirrhosis
(1) black sesame porridge pachyman: 10 grams black sesame, Poria 15 grams, ginger 3, 100 grams of rice. The ginger and cut into slices pachyman mashed, soaked for half an hour afterȡҩ֭were fried twice. Will two broth mixture, then cooked with rice and sesame seeds forϡ. for taking early supper, with ascites were good effect.
(2) Lily: Lily 60 grams, 100 grams of rice, ginger 3. Will Lily Wash chopped,with rice and can be used for early, taking supper, ascites, when available.
(3) lotus leaf medicine Hui duck soup: lotus leaves 50 grams, 500 grams of fresh duck meat, medicine Ren 100 grams. Will seldom washed, chopped into pieces of duck with lotus leaf medicine ren together, add water to rotten meat, do not salt and other spices, 2 times daily, each about 250 milliliters, and even served 1014 days, has diuretic, reducing the effect of the blood line of water.
(4) Elsholtzia: Elsholtzia 10 grams 50,100 grams rice. Elsholtzia first washed֭water to residue, then add rice. 2 times daily for morning and dinner with.
(5)СDongguashan Lei Tang: 1 fresh carp Treaty 500 grams,С100 grams, 200 grams Dongguashan. Will go fresh carp scales go after visceralСtogether with cooked to rare when Dongguashan add 200 grams, and then until the meat rotten soup of white, non-salt and other spices, cooked go after the filter residue with Sabu. 2 times daily, each serving about 250 milliliters, and even served 1014 days. can enhance plasma protein, has strong consumer Diuresis swelling effect.
(6) Garlic Steamed watermelon: 6090 grams of garlic, a watermelon about 15,002,000 grams.Ƥat first knife on a triangle of holes dug, garlic, peeled into the watermelon, the melon and then dredgedƤplugging holes willˮcooked up their hole.ȿto eat garlic and the West, while it is hot dose, garlic has anti-bacterial and anti-inflammatory effect, have watermelon Athermalisationconducive to water swelling function.
(7) steamed frog: Frog 250 grams, very light blue,all three grams, rice wine, salt, monosodium glutamate some. Will go visceral skinned frog into bowl, add appropriate amount of water, Add rice, green onions, ginger, salt, until known to use fire.consumption, has the role ofdiuresis.
(8) Fort Nanzaoeggs: Nanzao 10, West 30 grams of Lycium barbarum, eggs 2. The Chinese wolfberry, Nanzao amount of water after the wash, the1 hour later into the eggs,moment, made poached accompli. 2 times daily,Ե. forLiver Bushen. (9) soft-shelled turtle stewed yam longans: yam tablets 30 grams, 20 grams of meat longans, a soft-shelled turtle (about 500 grams). first Turtle at 45 warm water to make its scheduled urine, go aftermiscellaneous intestinal and head claw; And even with the meat, add water, a moderate, and yam, clear beef broth to the meat known to longans.meat and deficiency are suitable.
(10) Jujuba Shouwu boiled egg: 20 grams Shouwu, jujube 10, eggs 2. Will Shouwu, jujube, eggs, add water, adequateͬ, eggs cooked peeledafter, the decoction to 1 bowl, seasoning and then go dregs. day one timesԵ, even serving 15 days for 20 days. liver and stomach.
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